Good News for Infertility Patients with low AMH Levels

With our acupuncture and Chinese herbal treatment, we’ve been able to help many patients ranging from ages 40 -45 to conceive naturally as well as countless younger couples aged from 25 to 39. However, our biggest achievement in infertility treatment was in aiding a fifty-one year old patient in conceiving and delivering two now healthy four year old identical twins at age 52. 

This was not accomplished in brevity however. 

The patient approached our office six years prior. In consulting both with the patient and spouse, the methods chosen to help induce fertility were acupuncture and Chinese herbal medicine. As directed, she faithfully followed suit and saw progress multiple times naturally but without result, as she unfortunately miscarried at ages 45, 46, and 49. The consistent incident of loss was soon discovered to be attributed to fibroids, which we did not realize until then. Regardless, she still pursued a child. With that, an IVF specialist was consulted and discovered her eggs were of poor quality and  recommended she use a donor’s egg, which led her to have twins.

But if the above story happened today, the patient may not have needed to use the donor’s egg but her supposedly failed eggs instead. Dr. Renwang Xue, a professor at Stanford University, published an article in the Journal of American National Science Institute on September 30th, 2013 that explores a new method–In Vitro Activation (IVA) in treating patients with infertility issues between the ages of 40-45 as well as ovarian failure.

Generally speaking, each woman has 800,000 primary follicles in their ovaries from birth. However, only about 400 are fully developed within ones lifetime. Typically once a women has hit her 50’s, or as soon as menopause occurs, the development of these follicles will almost cease completely. The same odds are also a reality for those dealing with ovarian failure, as reproduction is highly unattainable, which is why most women cannot or don’t attempt to bear children post menopause. What they found was if they treat the ovary with a special procedure and then the primary follicles can continue to develop until it is fully capable of fertilization.

As previously stated, there are a vast amount of follicles located within the ovaries, however only a specific number are selected during the reproductive cycle. This limitation is caused by an enzyme known as the Phosphatase and Tensini Homolog (PTEN) gene, which acts as an inhibitor, causing the remainder of primary follicles to lay dormant. Liu etc. realized in order to increase the number of follicles selected, the PTEN gene must be genetically removed. Once the gene is terminated, discrimination among the selection of primary follicles is gone and the rate of fertility drastically increases.

Dr. Xue, building upon this discovery, figured instead of applying a genetic method of removing the PTEN gene, the same enzyme’s inhibitor can be manipulated to increase the amount of the primary follicle selected and still receive the same results. In this way, more matured follicles can be developed.

Based on the tested animal results, Dr. Xue then applied this idea to the human body. This new found method included activating the primary follicle and then placing them back into the ovaries, allowing them to grow for six months. After this, the fully matured follicle is taken out, and the method of IVF is applied. So far there has been a successful story.

Of course, the procedure is still very much so at the beginning stages. Nonetheless, it’s a promising start and a great hope for those formerly limited by their conditions and age.

Many People, Including Professionals, Still Don’t Know Acupuncture is Good for Infertility

Like anything else, when it comes to the topic of acupuncture everyone has an opinion. It’s scientifically proven that acupuncture can help or cure many diseases and conditions, but still many people don’t believe it. For acupuncture for infertility, tremendous scientific research has been done in China over the past 60 years indicating that it can affect our body in every way such as molecular, cell, tissue and system levels, etc. through regulating the nerve system and the endocrine system directly or indirectly, specifically the reproductive system such as ovary function, pituitary gland and adrenal gland function etc. The details can be found in the book Scientific Foundations of Acupuncture and Moxibustion by Zhu Bing Ph.D (Qing Dao 1998). There are many more books and publications about it, this book is just one example.

Many countries have started to use acupuncture for medical purposes. The National Institute of Health (NIH) of the U.S. Department of Health & Human Services published a Consensus Development Statement on acupuncture in 1997, which concluded that acupuncture can help many diseases and conditions. About 10 years ago, there was research done in Europe that stated acupuncture increases the pregnancy rate at a 50% chance. However in recent years, a study stated acupuncture can only relax people instead of helping them become pregnant.

There are many theories in medical fields that continuously change over time, depending on the latest developments. Take the CPR procedure and the principal of dealing with shock patients for example, these theories go back and forth, proving and disproving each other as the time goes on. We don’t think one or two scientific studies are able to represent the whole truth about acupuncture for infertility. The reality of acupuncture helping infertility issues in daily practice indicates that it works very well, otherwise acupuncture clinics for infertility wouldn’t have survived.

In the past years, just like other clinics, we have helped many infertility patients conceive with acupuncture and Chinese herbs treatment without IVF or IUI, aged from 30 to 45. Some of them are diagnosed by other specialists that they can not pregnant naturally or at all in their life time. We even helped patients get pregnant naturally with our protocol at ages 45, 47 and even 49.

Our first patient of this kind was a 35 year old woman from Brazil. In the initial visit, she told us her OB/GYN and the IVF specialist informed her that she will never get pregnant, according to her situation. After consultation and examination with Traditional Chinese Medicine (TCM) methodologies, we concluded that she was not hopeless and she still had a good chance to get pregnant naturally. After 15 sessions of acupuncture treatment with TCM herbs, within two months she became pregnant naturally. Twelve months later, she surprised me by coming to my office with her baby in the stroller. She told everyone in the office that we made the impossible possible. This patient is just one of many examples. We’ve also helped many M.D.’s themselves from different medical specialties in different medical facilities, such as: New York Presbyterian Hospital, Mount Sinai Medical School Hospital, New York Hospital, etc. to become pregnant in similar ways. One of our physician patients from New York Hospital was referred to us by her patient, who got pregnant by our acupuncture treatment, after experiencing three failed IVF procedures. We found that she had an irregular period, and was always tired with ice cold extremities, which means her hormones were imbalanced. We told her to stop trying IVF until her body was ready in terms of TCM diagnosis. Within two months she had 12 acupuncture sessions. Her period was regulated and she stopped experiencing ice cold extremities. We suggested that she should continue acupuncture treatments with IVF procedures, and in four months she was pregnant. Ten months later she gave birth to a healthy baby. Some physicians have tried IVF as many as five times without any results. Many of them after combining IVF with acupuncture treatment became pregnant too. We’ve had a patient from Australia that told us she tried IVF 18 times without any results, which is far too many times for one person to try. If the body is not well balanced and not ready, it is useless to try IVF again and again.

In the last 40 days, at our clinic, we’ve had four out of the seven couples we treated get pregnant. Three of these couples became pregnant naturally, at ages 34-37, who had been heading for IVF procedures. One couple had 12 acupuncture sessions and became pregnant within two months, the second couple got pregnant in the 3rd month, the third couple tried 24 sessions and within four months they were pregnant.

To understand why acupuncture can help infertility we must first become familiar with Chinese culture and tradition. One of the most important rules in Chinese culture and the tradition is: you must reproduce. Otherwise, it’s a sign of disrespect to your parents, family and ancestors. Essentially, you would be blamed for discontinuing the family lineage. Therefore, one of the important duties for Chinese doctors is to help patients conceive and have their own babies. This kind of practice dates back at least 2,000 years. Chinese doctors have spent centuries developing methodologies for infertility issues in both men and women. The procedures for female reproductive health include the care of: menstruation, pregnancy, breast feeding/lactation, inducing labor, and diseases and conditions related to postpartum; while for males this includes: ED, ejaculation problems etc. According to TCM and acupuncture theory, unless your missing an essential organ(s), some fundamentals to becoming pregnant as a woman are a healthy body and a regular and normal menstrual cycle etc.

Last year there was a book published in China by a colleague of mine from medical school. After reading the book I realized we have similar experiences regarding infertility issues with Chinese medicine and acupuncture. The book gives us many examples of cases labeled by specialists as ‘impossible’ without the help of IVF who got pregnant naturally with acupuncture and Chinese herbs treatments. I couldn’t agree more with one point of view from the book that the lab results are one thing, but the balance of the body is another. As long as the body is well balanced the lab results are not the most important as what is supposed to be, at least in terms of infertility issues. Otherwise there shouldn’t be so many so called impossible patients eventually getting pregnant and having healthy babies.

Nowadays, specifically in the United States, the cause of infertility for women, according to our clinical experience – apart from having organ problems – are: stress, aging, too low Anti-Müllerian Hormone (AMH) etc. Other factors include an imbalance of hormones due to diet, drugs, and other related diseases such as thyroid problems etc. If the related diseases and conditions are not our specialty, we do refer the patient to corespondent specialists. We found that many of our patients do not have a clear picture about their infertility issues even after seeking treatment from other infertility specialists. We also found from our patients some infertility specialists, do not suggest to see acupuncturists for help. We don’t know why, maybe because they don’t have enough information about acupuncture as a beneficial infertility treatment. Whatever it is, professionally and morally for the patient’s benefit it is fair to let the patients try acupuncture or combine acupuncture with IVF treatments. We truly believe from clinical experience that to let the patient understand what we are doing is important. If the patient cannot get the whole picture of this process, the results of the treatment will be poor. We also truly believe that the cooperation between patient and doctor is very important. That is why, in our clinic, when we see patients we always give them a clear picture of the whole procedure in a very detailed way according to our knowledge and experience, then the patients can comply.

The most unique part of Chinese medicine, for thousands of years, is the pure trial and error based only on human beings without the testing on animals. That is why the principals and treatments of TCM and acupuncture, some people believe, are closer to the reality of human being’s diseases and conditions. Many Chinese follow the Chinese medicine rules in their daily life activities for well being and to maintain their well being, especially, when they have medical problems such as infertility and it’s related problems. That is why some people say that Chinese medicine and acupuncture contribute to the Chinese population, obviously it shows today with its large size.